Chloroquine-induced lipidosis mimicking Fabry disease
نویسندگان
چکیده
منابع مشابه
Hydroxychloroquine-induced lipidosis of the kidney mimicking Fabry disease: a case report
A 51-year-old female patient with Sjogren’s syndrome had a renal insufficiency after 2 months’ history of hydroxychloroquine therapy (300 mg/d, cumulative dose of about 18 g). The renal biopsy suggested Fabry disease. The gene analysis and plasma a-galactosidase A activity were in the normal range. After quitting the therapy of hydroxychloroquine, the renal function returned to its normal state...
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Fabry disease is a rare X-linked inborn error of the glycosphingolipid metabolism caused by deficient activity of lysosomal enzyme alpha-galactosidase A. It is characterized by progressive multisystemic involvement that leads to premature death due to major organ failure, particularly the kidneys and heart. It appears that the disease is underdiagnosed in patients with end-stage renal disease. ...
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Fabry disease (FD) is a progressive, X-linked inherited disorder of glycosphingolipid metabolism due to deficient or absent lysosomal α-galactosidase A activity. FD is pan-ethnic and the reported annual incidence of 1 in 100,000 may underestimate the true prevalence of the disease. Classically affected hemizygous males, with no residual α-galactosidase A activity may display all the characteris...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2004
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.3800344